Product Overview
Tecovirimat | T17026 | TargetMol Chemicals
CAS: 869572-92-9
Smiles: [H][C@]12C[C@@]1([H])[C@@]1([H])C=C[C@]2([H])[C@]2([H])C(=O)N(NC(=O)c3ccc(cc3)C(F)(F)F)C(=O)[C@]12[H]
Formula: C19H15F3N2O3
Pathway: Proteases/Proteasome
Target: Cysteine Protease
Receptor: N/A
Bioactivity: Tecovirimat is a core protein cysteine protease inhibitor potentially for treatment of smallpox infection.Tecovirimat is a novel antiviral potent and selective activity against multiple orthopoxviruses (EC50: about 10 nM). that inhibits the egress of orthopoxviruses by targeting viral p37 protein orthologs.Tecovirimat has shown efficacy in all small animal and nonhuman primate prophylaxis and therapeutic efficacy models of poxvirus-induced disease tested to date.
Molecular Weight: 376, 335
