Product Overview
Tenovin-1 | T1919 | TargetMol Chemicals
CAS: 380315-80-0
Smiles: CC(=O)Nc1ccc(NC(=S)NC(=O)c2ccc(cc2)C(C)(C)C)cc1
Formula: C20H23N3O2S
Pathway: Apoptosis|||Autophagy|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Metabolism
Target: Mdm2|||Dehydrogenase|||Sirtuin|||p53|||Autophagy
Receptor: N/A
Bioactivity: Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination.
Molecular Weight: 369, 48
