Product Overview
Tepoxalin | T7724 | TargetMol Chemicals
CAS: 103475-41-8
Smiles: COc1ccc(cc1)-n1nc(CCC(=O)N(C)O)cc1-c1ccc(Cl)cc1
Formula: C20H20ClN3O3
Pathway: Immunology/Inflammation|||Metabolism|||Neuroscience
Target: Lipoxygenase|||COX
Receptor: N/A
Bioactivity: Tepoxalin is a 5-lipoxygenase inhibitor potentially for the treatment of asthma, osteoarthritis. Tepoxalin inhibits COX-1, COX-2, and 5-LOX. Tepoxalin is a potent inhibitor of sheep seminal vesicle cyclooxygenase (COX) (IC50 = 4.6 microM), rat basophilic leukemia cell (RBL-1) lysate COX (IC50 = 2.85 microM) and COX from intact RBL-1 cells (IC50 = 4.2 microM).
Molecular Weight: 385, 85