Product Overview
Tertiapin-Q | TP2114 | TargetMol Chemicals
CAS: 910044-56-3
Smiles:
Formula: C106H175N35O24S4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: A high affinity blocker for inward-rectifier K+ channels, this compound is a stable derivative of the bee venom toxin tertiapin. Binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are 1.3 and 13.3 nM respectively) and is selective over Kir2.1 channels. Derivative tertiapin LQ also available.
Molecular Weight: 2452
