Product Overview
Tesaglitazar | T17044 | TargetMol Chemicals
CAS: 251565-85-2
Smiles: O=C(O)[C@@H](OCC)CC1=CC=C(OCCC2=CC=C(OS(=O)(C)=O)C=C2)C=C1
Formula: C20H24O7S
Pathway: DNA Damage/DNA Repair|||Metabolism
Target: PPAR
Receptor: N/A
Bioactivity: Tesaglitazar causes interstitial mesenchymal cell DNA synthesis and fibrosarcomas in subcutaneous tissues in rats. Tesaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha/gamma agonist that is more potent on PPARγ than on PPARα (EC50s: 13.4 μM and 3.6 μM for rat PPARα and human PPARα, respectively).
Molecular Weight: 408, 47
