Product Overview
Tetrahydrouridine | T17059 | TargetMol Chemicals
CAS: 18771-50-1
Smiles: OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N1CCC(O)NC1=O
Formula: C9H16N2O6
Pathway: Chromatin/Epigenetic
Target: DNA Methyltransferase
Receptor: N/A
Bioactivity: Tetrahydrouridine (THU) is a multidrug resistance modulator. It can be used in cancer treatment to make tumor cells more sensitive to radiation therapy. THU is a competitive cytidine deaminase(CDA) inhibitor that inhibits deamination in the catabolism of cytotoxic deoxycytidine analogs such as ara-C and Gemcitabine.
Molecular Weight: 248, 235