Product Overview
Tezampanel (anhydrous) | T28955 | TargetMol Chemicals
CAS: 154652-83-2
Smiles: O=C([C@H]1NC[C@]2([H])CC[C@H](CCC3=NN=NN3)C[C@]2([H])C1)O
Formula: C13H21N5O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Tezampanel is a competitive antagonist of the AMPA and kainate subtypes of the ionotropic glutamate receptor family, with selectivity for the GluR5 subtype of the kainate receptor. It has neuroprotective and anticonvulsant properties, the former of which may, at least in part, occur via blockade of calcium uptake into neurons. It suppresses both the withdrawal symptoms from morphine and other opioids, and the development of tolerance, as well as having antihyperalgesic and analgesic effects in its own right.
Molecular Weight: 279, 34
