Product Overview
Thalidomide-NH-C4-NH2 TFA | T18808 | TargetMol Chemicals
CAS: 2093387-50-7
Smiles: OC(=O)C(F)(F)F.NCCCCNc1cccc2C(=O)N(C3CCC(=O)NC3=O)C(=O)c12
Formula: C19H21F3N4O6
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Thalidomide-NH-C4-NH2 TFA (compound 29c) is an E3 ligase ligand-linker conjugate, and incorporates the Thalidomide based cereblon ligand and a linker. Thalidomide-NH-C4-NH2 TFA is used in PROTAC BRD2/BRD4 degrader-1. PROTAC BRD2/BRD4 degrader-1 is a potent and selective BET protein BRD4 and BRD2 degrader[1].
Molecular Weight: 458, 394
