Product Overview
Thiomyristoyl | T3447 | TargetMol Chemicals
CAS: 1429749-41-6
Smiles: CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1
Formula: C34H51N3O3S
Pathway: Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: Sirtuin
Receptor: N/A
Bioactivity: Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.
Molecular Weight: 581, 86