Product Overview
Timegadine | T13160 | TargetMol Chemicals
CAS: 71079-19-1
Smiles: Cc1cc(\N=C(/NC2CCCCC2)Nc2nccs2)c2ccccc2n1
Formula: C20H23N5S
Pathway: Immunology/Inflammation|||Neuroscience
Target: COX
Receptor: N/A
Bioactivity: Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates and in washed rabbit platelets.
Molecular Weight: 365, 5