Product Overview
Tinoridine hydrochloride | T4313 | TargetMol Chemicals
CAS: 25913-34-2
Smiles: Cl.CCOC(=O)c1c(N)sc2CN(Cc3ccccc3)CCc12
Formula: C17H21ClN2O2S
Pathway: Immunology/Inflammation|||Metabolism|||Neuroscience
Target: COX|||Glutathione Peroxidase
Receptor: N/A
Bioactivity: Tinoridine (Y-3642) is a non-steroidal anti-inflammatory drug. Tinoridine (5-100 μM), produced a concentration-dependent inhibition on the simultaneous increases in lipid peroxide formation and renin release induced by 50 μM ascorbic acid in the renin granule fraction. On the other hand, indomethacin, hydrocortisone, and prednisolone, which had no ability to inhibit the lipid peroxidation in the renin granule fraction, did not influence the release of renin from the granules. These results suggest that tinoridine suppresses renin release by inhibiting the oxidative disintegration of membranes of renin granules.
Molecular Weight: 352, 88
