Product Overview
TIQ-A | T50098 | TargetMol Chemicals
CAS: 420849-22-5
Smiles: O=c1[nH]c2sccc2c2ccccc12
Formula: C11H7NOS
Pathway: Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: PARP
Receptor: N/A
Bioactivity: TIQ-A is a PARP1 inhibitor which involved in DNA single-strand break repair via the base excision repair pathway. PARP1 is triggered by DNA damage and its excessive activation has been proposed as a causative factor in many pathological conditions including ischemia and reperfusion injury, asthma-related inflammation, and atherogenesis.
Molecular Weight: 201, 244
