Product Overview
TL02-59 | T13186 | TargetMol Chemicals
CAS: 1315330-17-6
Smiles: CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(Oc4ncnc5cc(OC)c(OC)cc45)c3)cc2C(F)(F)F)CC1
Formula: C32H34F3N5O4
Pathway: Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||Src|||Hck
Receptor: N/A
Bioactivity: TL02-59 is a selective inhibitor of Fgr in Src-family kinase (IC50 = 0.03 nM). TL02-59 inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 potently suppresses acute myelogenous leukemia cell growth.
Molecular Weight: 609, 65
