Product Overview
TLR3-IN-1 | T22698 | TargetMol Chemicals
CAS: 1279713-77-7
Smiles: [H][C@](Cc1ccccc1)(\N=C(/O)c1sc2cc(F)ccc2c1Cl)C(O)=O
Formula: C18H13ClFNO3S
Pathway: Immunology/Inflammation
Target: TLR
Receptor: N/A
Bioactivity: CU CPT 4a is a selective TLR3 inhibitor (IC50: 3.44 μM in RAW 264.7 cells). It can inhibit TLR3/dsRNA complex-mediated downstream signaling pathways and inhibit the production of TNF-α and IL-1β in whole cells.
Molecular Weight: 377, 81
