Product Overview
TM608 | T34892 | TargetMol Chemicals
CAS: 1956343-52-4
Smiles: [Br-].Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc2c(Cl)cccc2Cl)c(C)c1C(=O)NCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1
Formula: C43H37BrCl2N3O4PS
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: TM608 is a potent selective c-Met inhibitor that targets mitochondria and kills erlotinib-resistant lung cancer cells, rapidly accumulates in mitochondria, and inhibits MET activation in high MET expression, erlotinib-resistant HCC827B cells (total cell lysates and mitochondrial portions).
Molecular Weight: 873, 62
