Product Overview
Toceranib | T13178 | TargetMol Chemicals
CAS: 356068-94-5
Smiles: Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NCCN1CCCC1
Formula: C22H25FN4O2
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: VEGFR|||PDGFR|||c-Kit
Receptor: N/A
Bioactivity: Toceranib phosphate is an orally active inhibitor of tyrosine kinase (RTK) receptor, and it potently inhibits PDGFR, VEGFR, and Kit(with Kis of 5 and 6 nM for PDGFRβ and Flk-1/KDR, respectively), has antitumor and antiangiogenic activity.
Molecular Weight: 396, 466
