Product Overview
Torin 1 | T6045 | TargetMol Chemicals
CAS: 1222998-36-8
Smiles: CCC(=O)N1CCN(CC1)c1ccc(cc1C(F)(F)F)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1cnc2ccccc2c1
Formula: C35H28F3N5O2
Pathway: Autophagy|||DNA Damage/DNA Repair|||PI3K/Akt/mTOR signaling
Target: DNA-PK|||PI3K|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.
Molecular Weight: 607, 637