Product Overview
Torkinib | T2414 | TargetMol Chemicals
CAS: 1092351-67-1
Smiles: CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc12
Formula: C16H16N6O
Pathway: Apoptosis|||Autophagy|||PI3K/Akt/mTOR signaling
Target: Apoptosis|||Mitophagy|||PI3K|||mTOR|||Autophagy
Receptor: N/A
Bioactivity: Torkinib (PP 242) is a selective and ATP-competitive mTOR inhibitor (IC50: 8 nM). It also inhibits mTORC1/2 (IC50s: 30/58 nM).
Molecular Weight: 308, 345