Product Overview
Tos-PEG4-t-butyl ester | T17133 | TargetMol Chemicals
CAS: 217817-01-1
Smiles: Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCC(=O)OC(C)(C)C
Formula: C20H32O8S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) is a PROTAC linker, which refers to the PEG composition. Tos-PEG4-t-butyl ester (Tos-PEG4-Boc) can be used in the synthesis of a series of PROTACs, such as BI-3663. BI-3663 is a highly selective PTK2/FAK PROTAC, with cereblon ligands to hijack E3 ligases for PTK2 degradation, and inhibits PTK2 with an IC50 of 18 nM[1].
Molecular Weight: 432, 53
