Product Overview
Trabectedin | T17155 | TargetMol Chemicals
CAS: 114899-77-3
Smiles: [H][C@@]12[C@@H]3SC[C@]4(NCCc5cc(O)c(OC)cc45)C(=O)OC[C@H](N1[C@@H](O)[C@@H]1Cc4cc(C)c(OC)c(O)c4[C@H]2N1C)c1c2OCOc2c(C)c(OC(C)=O)c31
Formula: C39H43N3O11S
Pathway: Apoptosis|||Immunology/Inflammation|||Metabolism|||NF-Κb
Target: Apoptosis|||Reactive Oxygen Species
Receptor: N/A
Bioactivity: Trabectedin has potent antitumor activity and the potential for soft tissue sarcoma and ovarian cancer research. Trabectedin inhibits cell growth of MX-1, MCF7 and MCF7/DXR cells with IC50 values of 0.1 nM, 1.5 nM and 3.7 nM, respectively.
Molecular Weight: 761, 84
