Product Overview
TRAM-34 | T6186 | TargetMol Chemicals
CAS: 289905-88-0
Smiles: Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1cccn1
Formula: C22H17ClN2
Pathway: Membrane transporter/Ion channel|||NF-Κb
Target: Potassium Channel|||IκB/IKK
Receptor: N/A
Bioactivity: TRAM-34(Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450. The selective activity of TRAM-34 is 200 to 1500-fold than other ion channels.
Molecular Weight: 344, 84