Product Overview
TRi-1 | T5481 | TargetMol Chemicals
CAS: 246020-68-8
Smiles: COc1ccc(c(n1)S(=O)(=O)c1ccc(Cl)cc1)[N+]([O-])=O
Formula: C12H9ClN2O5S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy
Molecular Weight: 328, 72
