Trichlormethiazide | T0114

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TMC-T0114
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Product Overview

Trichlormethiazide | T0114 | TargetMol Chemicals

CAS: 133-67-5

Smiles: NS(=O)(=O)c1cc2c(NC(NS2(=O)=O)C(Cl)Cl)cc1Cl

Formula: C8H8Cl3N3O4S2

Pathway: Membrane transporter/Ion channel|||Metabolism

Target: ATPase|||Carbonic Anhydrase

Receptor: N/A

Bioactivity: Trichlormethiazide is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.

Molecular Weight: 380, 64

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