Product Overview
Trifluridine | T1428 | TargetMol Chemicals
CAS: 70-00-8
Smiles: OC[C@H]1O[C@H](C[C@@H]1O)n1cc(c(=O)[nH]c1=O)C(F)(F)F
Formula: C10H11F3N2O5
Pathway: Cell Cycle/Checkpoint|||DNA Damage/DNA Repair|||Microbiology/Virology
Target: Nucleoside Antimetabolite/Analog|||DNA/RNA Synthesis|||HSV
Receptor: N/A
Bioactivity: Trifluridine is a fluorinated thymidine analog with potential antineoplastic activity. Trifluridine is incorporated into DNA and inhibits thymidylate synthase, resulting in inhibition of DNA synthesis, inhibition of protein synthesis, and apoptosis. This agent also exhibits antiviral activity.
Molecular Weight: 296, 202
