Product Overview
Triparanol | T26296 | TargetMol Chemicals
CAS: 78-41-1
Smiles: CCN(CC)CCOc1ccc(cc1)C(O)(Cc1ccc(Cl)cc1)c1ccc(C)cc1
Formula: C27H32ClNO2
Pathway: GPCR/G Protein|||Stem Cells
Target: Hedgehog/Smoothened
Receptor: N/A
Bioactivity: Triparanol interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic toxicity.
Molecular Weight: 438, 01