Product Overview
Trk-IN-4 | T17169 | TargetMol Chemicals
CAS: 1799788-94-5
Smiles: Cn1cnc(c1)-c1cnc(O[C@H]2CCN(C[C@H]2F)C(=O)Cc2ccc(OC(F)(F)F)cc2)c(c1)C(N)=O
Formula: C24H23F4N5O4
Pathway: Tyrosine Kinase/Adaptors
Target: Trk receptor
Receptor: N/A
Bioactivity: Trk-IN-4 is an effective pan-Trk inhibitor in cell-based assays (IC50s: 1.9 nM, 2.6 nM, and 1.1 nM for TrkA, TrkB, and TrkC, respectively).
Molecular Weight: 521, 473