Product Overview
Tyrphostin AG 879 | T6712 | TargetMol Chemicals
CAS: 148741-30-4
Smiles: CC(C)(C)c1cc(\C=C(/C#N)C(N)=S)cc(c1O)C(C)(C)C
Formula: C18H24N2OS
Pathway: Angiogenesis|||Apoptosis|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||EGFR|||Trk receptor|||HER|||PDGFR
Receptor: N/A
Bioactivity: Tyrphostin AG 879 effectively inhibits HER2/ErbB2 (IC50: 1 μM), 100- and 500-fold higher selective to ErbB2 than EGFR and PDGFR.
Molecular Weight: 316, 46
