Product Overview
Ulixertinib hydrochloride | T7005L | TargetMol Chemicals
CAS: 1956366-10-1
Smiles: O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO.[H]Cl
Formula: C21H23Cl3N4O2
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: Ulixertinib is an inhibitor of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival.
Molecular Weight: 469, 79
