Product Overview
Umbralisib hydrochloride | T17066 | TargetMol Chemicals
CAS: 1532533-78-0
Smiles: Cl.CC(C)Oc1ccc(cc1F)-c1nn([C@@H](C)c2oc3ccc(F)cc3c(=O)c2-c2cccc(F)c2)c2ncnc(N)c12
Formula: C31H25ClF3N5O3
Pathway: PI3K/Akt/mTOR signaling
Target: PI3K
Receptor: N/A
Bioactivity: Umbralisib hydrochloride is a novel PI3Kδ inhibitor (IC50 and EC50 of 22.2 nM and 24.3 nM, respectively). Umbralisib hydrochloride is also active against CK1ε (EC50: 6.0 μM).
Molecular Weight: 608, 02
