Product Overview
Umibecestat | T13253 | TargetMol Chemicals
CAS: 1387560-01-1
Smiles: C[C@]1(CO[C@](C)(C(N)=N1)C(F)(F)F)c1nc(NC(=O)c2ncc(cc2Cl)C(F)(F)F)ccc1F
Formula: C19H15ClF7N5O2
Pathway: Neuroscience
Target: BACE
Receptor: N/A
Bioactivity: Umibecestat is an inhibitor of beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1), with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Umibecestat can be used for the research of alzheimer's disease.
Molecular Weight: 513, 8
