Product Overview
Uprosertib | T6849 | TargetMol Chemicals
CAS: 1047634-65-0
Smiles: Cn1ncc(Cl)c1-c1cc(oc1Cl)C(=O)N[C@H](CN)Cc1ccc(F)c(F)c1
Formula: C18H16Cl2F2N4O2
Pathway: Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling
Target: Akt
Receptor: N/A
Bioactivity: Uprosertib (GSK2141795) is a selective, ATP-competitive, and orally bioavailable Akt inhibitor with IC50 of 180 nM, 328 nM, and 38 nM for Akt 1, 2 and 3, respectively. Phase 2.
Molecular Weight: 429, 25
