Product Overview
Ureidopropionic acid | T4919 | TargetMol Chemicals
CAS: 462-88-4
Smiles: NC(=O)NCCC(O)=O
Formula: C4H8N2O3
Pathway: Metabolism
Target: Endogenous Metabolite
Receptor: N/A
Bioactivity: Ureidopropionic acid is an intermediate in the metabolism of uracil. More specifically it is a breakdown product of dihydrouracil and is produced by the enzyme dihydropyrimidase. It is further decomposed to beta-alanine via the enzyme beta-ureidopropionase. Ureidopropionic acid is essentially a urea derivative of beta-alanine. High levels of Ureidopropionic acid are found in individuals with beta-ureidopropionase (UP) deficiency. Enzyme deficiencies in pyrimidine metabolism are associated with a risk for severe toxicity against the antineoplastic agent 5-fluorouracil.
Molecular Weight: 132, 119
