Product Overview
UT-34 | T13273 | TargetMol Chemicals
CAS: 2168525-92-4
Smiles: C[C@](O)(Cn1cc(F)cn1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F
Formula: C15H12F4N4O2
Pathway: Endocrinology/Hormones
Target: Androgen Receptor
Receptor: N/A
Bioactivity: UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prostate cancer efficacy.
Molecular Weight: 356, 281