Product Overview
Vactosertib Hydrochloride | T15262 | TargetMol Chemicals
CAS: 1352610-25-3
Smiles: Cl.Cc1cccc(n1)-c1nc(CNc2ccccc2F)[nH]c1-c1ccc2ncnn2c1
Formula: C22H19ClFN7
Pathway: Angiogenesis|||Tyrosine Kinase/Adaptors
Target: ALK
Receptor: N/A
Bioactivity: Vactosertib Hydrochloride is an orally active and ATP-competitive ALK5 inhibitor (IC50: 12.9 nM). It has potently antimetastatic activity and anticancer effect. Vactosertib Hydrochloride also inhibits ALK2 and ALK4 (IC50: 17.3 nM).
Molecular Weight: 435, 89
