Product Overview
Vacuolin-1 | T21992 | TargetMol Chemicals
CAS: 351986-85-1
Smiles: Ic1cccc(\C=N\Nc2nc(nc(n2)N2CCOCC2)N(c2ccccc2)c2ccccc2)c1
Formula: C26H24IN7O
Pathway: Autophagy|||PI3K/Akt/mTOR signaling
Target: PI3K|||Autophagy
Receptor: N/A
Bioactivity: Vacuolin-1 is a cell-permeable inhibitor of Ca2+ dependent fusion of lysosomes to the cell membrane. It acts by inhibiting release of lysosomal content.vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation
Molecular Weight: 577, 43
