Product Overview
Valproic Acid | T7064 | TargetMol Chemicals
CAS: 99-66-1
Smiles: CCCC(CCC)C(O)=O
Formula: C8H16O2
Pathway: Autophagy|||Chromatin/Epigenetic|||DNA Damage/DNA Repair|||Membrane transporter/Ion channel|||Microbiology/Virology|||Neuroscience|||Proteases/Proteasome|||Stem Cells
Target: Mitophagy|||Gamma-secretase|||HIV Protease|||GABA Receptor|||Sodium Channel|||HDAC|||Autophagy
Receptor: N/A
Bioactivity: Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various molecular mechanisms of action of Valproic Acid have not been completely elucidated. Valproic Acid has been reported to be a potent inhibitor of histone deacetylases (HDACs) in vitro. Valproic Acid is also noted to relieve HDAC-dependent transcriptional repression and causes the hyperacetylation of histones in cultured cells. Additionally, Valproic Acid is reported to activate Wnt-dependent gene expression and to mimic trichostatin A (sc-3511) in the inhibition of histone deacetylase.
Molecular Weight: 144, 214
