Product Overview
Vandetanib | T1656 | TargetMol Chemicals
CAS: 443913-73-3
Smiles: COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1
Formula: C22H24BrFN4O2
Pathway: Angiogenesis|||Apoptosis|||Autophagy|||JAK/STAT signaling|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||EGFR|||VEGFR|||Autophagy
Receptor: N/A
Bioactivity: Vandetanib is a potent inhibitor of VEGFR2 (IC50: 40 nM). It also inhibits VEGFR3 and EGFR.
Molecular Weight: 475, 362
