Product Overview
Vatalanib dihydrochloride | T6720 | TargetMol Chemicals
CAS: 212141-51-0
Smiles: Cl.Cl.Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Formula: C20H17Cl3N4
Pathway: Angiogenesis|||Apoptosis|||Tyrosine Kinase/Adaptors
Target: Apoptosis|||VEGFR|||PDGFR
Receptor: N/A
Bioactivity: Vatalanib (PTK787) (IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4.
Molecular Weight: 419, 73