Product Overview
Veliparib dihydrochloride | T2105 | TargetMol Chemicals
CAS: 912445-05-7
Smiles: Cl.Cl.C[C@@]1(CCCN1)c1nc2c(cccc2[nH]1)C(N)=O
Formula: C13H18Cl2N4O
Pathway: Autophagy|||Chromatin/Epigenetic|||DNA Damage/DNA Repair
Target: PARP|||Autophagy
Receptor: N/A
Bioactivity: Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM in cell-free assays, respectively. It is inactive to SIRT2.
Molecular Weight: 317, 21
