Product Overview
Venetoclax | T2119 | TargetMol Chemicals
CAS: 1257044-40-8
Smiles: CC1(C)CCC(CN2CCN(CC2)c2ccc(C(=O)NS(=O)(=O)c3ccc(NCC4CCOCC4)c(c3)[N+]([O-])=O)c(Oc3cnc4[nH]ccc4c3)c2)=C(C1)c1ccc(Cl)cc1
Formula: C45H50ClN7O7S
Pathway: Apoptosis|||Autophagy
Target: BCL|||Autophagy
Receptor: N/A
Bioactivity: ABT-199 is a selective inhibitor of Bcl-2 (Ki < 0.010 nM), binding over 3 orders of magnitude less avidly to Bcl-xL, and Bcl-W (Kis = 48 and 245 nM, respectively).
Molecular Weight: 868, 45
