Product Overview
Vismodegib | T2590 | TargetMol Chemicals
CAS: 879085-55-9
Smiles: CS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)c(c2)-c2ccccn2)c(Cl)c1
Formula: C19H14Cl2N2O3S
Pathway: Autophagy|||GPCR/G Protein|||Membrane transporter/Ion channel|||Stem Cells
Target: Hedgehog/Smoothened|||ABC|||Autophagy
Receptor: N/A
Bioactivity: Vismodegib is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).
Molecular Weight: 421, 29
