Product Overview
Vofopitant dihydrochloride | T13329L | TargetMol Chemicals
CAS: 168266-51-1
Smiles: Cl.Cl.COc1ccc(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)-n1nnnc1C(F)(F)F
Formula: C21H25Cl2F3N6O
Pathway: GPCR/G Protein|||Neuroscience
Target: Neurokinin receptor
Receptor: N/A
Bioactivity: Vofopitant dihydrochloride is a selective and orally available antagonist of tachykinin neurokinin 1(NK1) receptor (pKi: 9.5 and 10.6 in rat and human membranes respectively) and is a potential broad-spectrum anti-emetic agent.
Molecular Weight: 505, 37
