Product Overview
Volasertib | T6019 | TargetMol Chemicals
CAS: 755038-65-4
Smiles: CC[C@H]1N(C(C)C)c2nc(Nc3ccc(cc3OC)C(=O)N[C@H]3CC[C@@H](CC3)N3CCN(CC4CC4)CC3)ncc2N(C)C1=O
Formula: C34H50N8O3
Pathway: Apoptosis|||Cell Cycle/Checkpoint
Target: Apoptosis|||PLK
Receptor: N/A
Bioactivity: Volasertib (BI-6727) is a potent inhibitor of PLK1 (IC50: 0.87 nM), inducing mitotic arrest and apoptosis. It also inhibits PLK2/PLK3 (IC50s: 5/56 nM).
Molecular Weight: 618, 81
