Product Overview
VU0361737 | T6726 | TargetMol Chemicals
CAS: 1161205-04-4
Smiles: COc1cc(NC(=O)c2ccccn2)ccc1Cl
Formula: C13H11ClN2O2
Pathway: Neuroscience
Target: GluR
Receptor: N/A
Bioactivity: VU 0361737 is a specific positive allosteric modulator (PAM) of mGlu4 receptor.The EC50 of VU 0361737 is 240 nM for the human receptors. The EC50 of VU 0361737 is110 nM for rat receptors.It exhibits weak activity at mGlu5 and mGlu8 receptors, and is inactive at mGlu1, mGlu2, mGlu3, mGlu6 and mGlu7 receptors, can penetrate into CNS.
Molecular Weight: 262, 69