Product Overview
VU0467485 | T17245 | TargetMol Chemicals
CAS: 1451994-10-7
Smiles: COc1ccc(CNC(=O)c2sc3nnc(C)c(C)c3c2N)cc1F
Formula: C17H17FN4O2S
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: VU0467485 is a potent and selective muscarinic acetylcholine receptor 4 positive allosteric modulator. VU0467485 potentiates the activity of ACh at M4 (EC50s: 26.6 nM and 78.8 nM at the rat and human M4 receptors, respectively). VU0467485 displays selectivity for M4 over human and rat M1/2/3/5.
Molecular Weight: 360, 41
