Product Overview
VU0486321 | T35081 | TargetMol Chemicals
CAS: 1816301-67-3
Smiles: Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c(Cl)c1
Formula: C20H12ClFN2O4
Pathway: N/A
Target: N/A
Receptor: N/A
Bioactivity: VU0486321 is a potent mGlu1 PAM with moderate rat PK (CLp = 13.3. mL/min/kg, t1/2 = 54 min), good free fraction (human fu = 0.05, rat fu =0.03) and excellent CNS penetration (Kp = 1.02).
Molecular Weight: 398, 77