Product Overview
VU0650786 | T13318 | TargetMol Chemicals
CAS: 1809085-30-0
Smiles: C[C@@H]1CN(C(=O)c2cc(COc3ccc(Cl)cn3)nn12)c1cccnc1F
Formula: C18H15ClFN5O2
Pathway: Neuroscience
Target: GluR
Receptor: N/A
Bioactivity: VU0650786 is a selective and potent CNS penetrant negative allosteric modulator of metabotropic glutamate receptor subtype 3 (mGlu3 NAM) (IC50: 392 nM), with antidepressant and anxiolytic activity in rodents.
Molecular Weight: 387, 8