Product Overview
VZ185 | T17249 | TargetMol Chemicals
CAS: 2306193-61-1
Smiles: O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3OCCCCCN5CCN(CC6=C(OC)C=C(C(C7=CC=NC=C87)=CN(C)C8=O)C=C6OC)CC5
Formula: C53H67FN8O8S
Pathway: Chromatin/Epigenetic
Target: Epigenetic Reader Domain
Receptor: N/A
Bioactivity: VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively).
Molecular Weight: 995, 21