Product Overview
Wilforine | T6S1049 | TargetMol Chemicals
CAS: 11088-09-8
Smiles: C[C@H]1CCc2ncccc2C(=O)OC[C@]2(C)O[C@]34[C@H](OC(C)=O)[C@H]2[C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@]3(COC(C)=O)[C@@H](OC(C)=O)[C@@H](OC(=O)c2ccccc2)[C@H](OC1=O)[C@]4(C)O
Formula: C43H49NO18
Pathway: Membrane transporter/Ion channel
Target: ATPase
Receptor: N/A
Bioactivity: Wilforine is a sesquiterpene pyridine alkaloid; important bioactive compound in T. wilfordii plants, and is effective in treating idiopathic pulmonary fibrosis. Wilforine has anti-inflammatory effect, which might be mediated by down-regulation of the expression of inflammatory factors TNF-α, IL-6 and NO. It also has insecticidal activity by inhibiting the Na+-K+-ATPase in the central nervous system.
Molecular Weight: 867, 854