Product Overview
WR-99210 | T17257L | TargetMol Chemicals
CAS: 30711-93-4
Smiles: NC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl
Formula: C14H19Cl4N5O2
Pathway: Others
Target: Others
Receptor: N/A
Bioactivity: WR-99210 is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.
Molecular Weight: 431, 14
